If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.

It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.

Cover Image

Arthritis & Rheumatism

RSS feed for Arthritis & Rheumatism What is RSS?

Volume 52, Issue 11 , Pages 3515 - 3519

Published Online: 27 Oct 2005

Copyright © 2005 by the American College of Rheumatology

Journal Homepage Link
E-Mail and Print ToolbarE-MailPrint

Published on behalf of
American College of Rheumatology
Go to Society Site

 Research Article
Hip abduction moment and protection against medial tibiofemoral osteoarthritis progression
Alison Chang 1, Karen Hayes 1, Dorothy Dunlop 1, Jing Song 1, Debra Hurwitz 2, September Cahue 1, Leena Sharma 1 *
1Feinberg School of Medicine, Northwestern University, Chicago, Illinois
2Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois
email: Leena Sharma (L-Sharma@northwestern.edu)

*Correspondence to Leena Sharma, Division of Rheumatology, Feinberg School of Medicine, Northwestern University, 240 East Huron, Suite 2300, Chicago, IL 60611

Funded by:
 NIH; Grant Number: P60-AR-48098, R01-48748, R01-AR-46225, RR-00048


To test the hypothesis that a greater peak internal hip abduction moment is associated with a reduced likelihood of ipsilateral medial tibiofemoral osteoarthritis (OA) progression.

Fifty-seven persons with knee OA (by definite osteophyte presence and symptoms) were evaluated. Baseline assessments included kinematic and kinetic gait parameters, obtained with an optoelectronic camera system and force platform, with inverse dynamics used to calculate 3-dimensional moments at the joints; pain, using a separate visual analog scale for each knee; and alignment, using full-limb radiographs. Radiographs of the knee in a semiflexed position, with fluoroscopic confirmation of tibial rim alignment, were obtained at baseline and 18 months later. Disease progression was defined as worsening of the grade of medial joint space narrowing. Logistic regression obtained with generalized estimating equations was used to estimate odds ratios (ORs) for progression per unit of hip abduction moment, after excluding knees with the worst joint space grade at baseline (which could not progress).

The 57 participants (63% women) with mild to moderate OA had a mean age of 67 years and a mean body mass index of 29. A greater internal hip abduction moment during gait was associated with a reduced likelihood of medial tibiofemoral OA progression, with OR/unit hip abduction moment of 0.52 and a 95% confidence interval (95% CI) of 0.32-0.85. This protective effect persisted after adjustment for age, sex, walking speed, knee pain severity, physical activity, varus malalignment severity, hip OA presence, and hip OA symptom presence, with an adjusted OR of 0.43 a 95% CI of 0.22-0.81.

A greater hip abduction moment during gait at baseline protected against ipsilateral medial OA progression from baseline to 18 months. The likelihood of medial tibiofemoral OA progression was reduced 50% per 1 unit of hip abduction moment.

Received: 25 March 2005; Accepted: 9 August 2005

Digital Object Identifier (DOI)

10.1002/art.21406  About DOI

Related Articles

  • Find other articles like this in Wiley InterScience
  • Find articles in Wiley InterScience written by any of the authors

Wiley InterScience is a member of CrossRef.

Cross Ref Memeber

Search For Articles In This Title

Arthritis & Rheumatism

Search By Citation

Sign Up Now
Wiley InterScience MobileEdition

Get select content from some of Wiley's leading publications delivered to your PDA — free!

Sign up now

Take part in User Survey for a Chance to win an iPod
Reprint Inquiries
Wiley InterScience Article Reprints
Need a reprint?

Paper or electronic reprints are available for all content published on Wiley InterScience. Inquiries can be submitted online.

Find out more about reprints

Now Available
General Medicine

 Wiley InterScience Backfile Collections

Fully searchable and live-linked with current web content, this backfile brings the complete contents of 20 leading journals, 62,500 articles, to your desktop. A one-time fee delivers ongoing access.

Find out more
Request a Quote

Essential Evidence Plus

all-the-time answers
at the point of care.

Subscribe Today!

Now Available
Backfiles on Pay-Per-View

 Wiley InterScience Backfile Collections

More than 600,000 journal articles starting at Volume 1, Issue 1, dating as far back as 1800s and spanning the disciplines of chemistry, life sciences, medicine and materials science are now available online for Pay-Per-View purchase on Wiley InterScience.

Browse Journals by Subject

EBM Guidelines

EBM Guidelines

(Evidence-Based Medicine)

The key source of practical information for primary care with the most extensive collection of concise treatment recommendations


Also of Interest

Musculoskeletal Care journals

Wiley publishes a full range of Musculoskeletal Care journals